hematopoietic system
• the number of kappa+ splenic B cells is reduced lowering the ratio of kappa to lambda B cells to a greater extent than in Igk-Eiktm1(Igh)Xu homozygotes
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immune system
• the number of kappa+ splenic B cells is reduced lowering the ratio of kappa to lambda B cells to a greater extent than in Igk-Eiktm1(Igh)Xu homozygotes
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