craniofacial
N |
• transgenic mice show complete rescue of cleft lip phenotype
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• at E18.5, bones of hard palate are reduced in size and show altered morphology
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• at E18.5, palatal processes of maxilla are reduced in size and show altered morphology
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• incidence of cleft secondary palate is reduced to 42% in non-transgenic homozygotes
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skeleton
• at E18.5, bones of hard palate are reduced in size and show altered morphology
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• at E18.5, palatal processes of maxilla are reduced in size and show altered morphology
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digestive/alimentary system
• at E18.5, bones of hard palate are reduced in size and show altered morphology
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• at E18.5, palatal processes of maxilla are reduced in size and show altered morphology
|
• incidence of cleft secondary palate is reduced to 42% in non-transgenic homozygotes
|
growth/size/body
• at E18.5, bones of hard palate are reduced in size and show altered morphology
|
• at E18.5, palatal processes of maxilla are reduced in size and show altered morphology
|
• incidence of cleft secondary palate is reduced to 42% in non-transgenic homozygotes
|