Phenotypes associated with this allele

• Allele Symbol: Gnao1^tm1Adhi
• Allele Name: targeted mutation 1, Anuradha Dhingra
• Allele ID: MGI:3759767
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gnao1^tm1Adhi/Gnao1^tm1Adhi	Not Specified	MGI:3759770

Genotype
MGI:3759770

hm1

• Allelic Composition: Gnao1^tm1Adhi/Gnao1^tm1Adhi
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal eye electrophysiology ( J:125588 )

• under scotopic, saturated and photopic conditions mice lack the b-wave

• however, the a-wave is present under scotopic, saturated and photopic conditions

• under the saturated condition, mice produce a reduced a wave of 78+/-34 uV

abnormal cone electrophysiology ( J:125588 )

• under the photopic condition, the negative wave (a combination of a-wave and OFF bipolar response) is as large or greater than in wild-type mice