Phenotypes associated with this allele

• Allele Symbol: Cdk8^{GT(RRS314)Byg}
• Allele Name: gane trap RRS314, BayGenomics
• Allele ID: MGI:3760076
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cdk8^GT(RRS314)Byg/Cdk8^GT(RRS314)Byg	involves: 129P2/OlaHsd * CD-1	MGI:3760078

Genotype
MGI:3760078

hm1

• Allelic Composition: Cdk8^{GT(RRS314)Byg}/Cdk8^{GT(RRS314)Byg}
• Genetic Background: involves: 129P2/OlaHsd * CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality before implantation, complete penetrance ( J:125327 )

• only 4 embryos are recovered at E2.5 and 1 at E3.0 indicating very early embryonic lethality

• embryos extracted from a superovulated female and grown in culture have a runted appearance and reduced viability at day 0.5

embryo

abnormal preimplantation embryo development ( J:125327 )

failure of morula compaction ( J:125327 )

• blastomeres are fragmented at the 8-cell stage and no embryo compaction is observed