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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Mylpf-cre)3Kraj
transgene insertion 3, Stan Krajewski
MGI:3761931
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Podxltm1Parl/Podxl+
Tg(Mylpf-cre)3Kraj/? 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * FVB/N MGI:4442893
cn2
 		Podxltm1Parl/Podxltm1Parl
Tg(Mylpf-cre)3Kraj/? 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * FVB/N MGI:4442896
tg3
 		Tg(Mylpf-cre)3Kraj/Tg(Mylpf-cre)3Kraj involves: FVB/N MGI:3762371


Genotype
MGI:4442893
cn1
Allelic
Composition		 Podxltm1Parl/Podxl+
Tg(Mylpf-cre)3Kraj/?
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Podxltm1Parl mutation (0 available); any Podxl mutation (17 available)
Tg(Mylpf-cre)3Kraj mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype




Genotype
MGI:4442896
cn2
Allelic
Composition		 Podxltm1Parl/Podxltm1Parl
Tg(Mylpf-cre)3Kraj/?
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Podxltm1Parl mutation (0 available); any Podxl mutation (17 available)
Tg(Mylpf-cre)3Kraj mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
enlarged brain ventricles ( J:158322 )
• the ventricular spaces were enlarged

cardiovascular system
abnormal carotid artery morphology ( J:158322 )
• the carotid arteries are thicker than the wild type control
abnormal capillary morphology ( J:158322 )
• increased number of capillaries lining the intraventricular spaces




Genotype
MGI:3762371
tg3
Allelic
Composition		 Tg(Mylpf-cre)3Kraj/Tg(Mylpf-cre)3Kraj
Genetic
Background		 involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Mylpf-cre)3Kraj mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:99342 )
• homozygous mice are viable and fertile; no phenotypic description is provided




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory