Phenotypes associated with this allele

• Allele Symbol: Grn^tm1Mni
• Allele Name: targeted mutation 1, Masugi Nishihara
• Allele ID: MGI:3762618
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Grn^tm1Mni/Grn^tm1Mni	involves: 129P2/OlaHsd * C57BL/6J	MGI:3762619

Genotype
MGI:3762619

hm1

• Allelic Composition: Grn^tm1Mni/Grn^tm1Mni
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

abnormal ejaculation ( J:126370 )

♂ • ejaculation incidence is decreased compared to wild-type or heterozygous males

♂ • the percentage of mice displaying ejaculation over the three trials is reduced compared to wild-type or heterozygous males

behavior/neurological

increased aggression towards male mice ( J:126370 )

• increase in the frequency of bite attacks in the third of three trials in the resident-intruder test

• however, no significant difference was seen in the first 2 trials

increased anxiety-related response ( J:126370 )

• males spend significantly less time in the center of an open field compared to wild-type males

• no sex-difference in the amount of time spent in the center of an open field is seen in mutants unlike wild-type mice