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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Prnptm4(PRNP)Tkit
targeted mutation 4, Tetsuyuki Kitamoto
MGI:3762786
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Prnptm4(PRNP)Tkit/Prnptm4(PRNP)Tkit Not Specified MGI:3762809
cx2
Prnptm4(PRNP)Tkit/Prnptm4(PRNP)Tkit
Tg(Prnp-PRNP)32Tkit/?
Not Specified MGI:3762808


Genotype
MGI:3762809
hm1
Allelic
Composition
Prnptm4(PRNP)Tkit/Prnptm4(PRNP)Tkit
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prnptm4(PRNP)Tkit mutation (0 available); any Prnp mutation (142 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• mice are highly susceptible to bovine spongiform encephalopathy and variant Creutzfeldt-Jakob prion infection
• however, mice are not susceptible to sporadic prion infection




Genotype
MGI:3762808
cx2
Allelic
Composition
Prnptm4(PRNP)Tkit/Prnptm4(PRNP)Tkit
Tg(Prnp-PRNP)32Tkit/?
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prnptm4(PRNP)Tkit mutation (0 available); any Prnp mutation (142 available)
Tg(Prnp-PRNP)32Tkit mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• mice are highly susceptible to bovine spongiform encephalopathy and variant Creutzfeldt-Jakob prion infection
• however, mice are not susceptible to sporadic or dura graft-associated prion infection





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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory