All Phenotypes Gcsam<tm1.1Rsky> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gcsam^tm1.1Rsky
targeted mutation 1.1, Klaus Rajewsky
MGI:3763735

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gcsam^tm1.1Rsky/Gcsam^tm1.1Rsky	involves: BALB/cJ * C57BL/6	MGI:3763737

Allelic Composition	Gcsam^tm1.1Rsky/Gcsam^tm1.1Rsky
Genetic Background	involves: BALB/cJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gcsam^tm1.1Rsky mutation (0 available); any Gcsam mutation (12 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

immune system phenotype ( J:125784 )

N	• no defects in germinal center formation, somatic hypermutation, or class switch recombination

decreased Peyer's patch number ( J:125784 )

• average number is 5.1 compared to 7.8 in wild-type controls

small Peyer's patches ( J:125784 )

• number of cells found per mouse is reduced by two-thirds

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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