Analysis Tools
immune system
|
• labeled splenocytes have slightly less migration rate to the small and large intestine after intravenous injection into congenic hosts
• migration is increased when splenocytes are pretreated with pertussis toxin
|
|
• splenocytes and memory T cells persistently exhibit firm adhesion to MadCAM coated surfaces even in presence of calcium ions that normally inhibit binding
• five fold more splenocytes are found to be "sticking" to Peyer's patch venules
|
|
• only a mild form of colitis develops when nave CD4 T cells from these mice are transferred to immunocompromised mice as opposed to the robust colitis that occurs when the T cells come from wild-type mice
• the number of transferred T cells found in the large intestine is reduced by half
|
|
• Peyer's patches are about 20% smaller in size
• they contain four fold less T cells and three fold less B cells
|
digestive/alimentary system
|
• only a mild form of colitis develops when nave CD4 T cells from these mice are transferred to immunocompromised mice as opposed to the robust colitis that occurs when the T cells come from wild-type mice
• the number of transferred T cells found in the large intestine is reduced by half
|
cellular
|
• labeled splenocytes have slightly less migration rate to the small and large intestine after intravenous injection into congenic hosts
• migration is increased when splenocytes are pretreated with pertussis toxin
|
|
• splenocytes and memory T cells persistently exhibit firm adhesion to MadCAM coated surfaces even in presence of calcium ions that normally inhibit binding
• five fold more splenocytes are found to be "sticking" to Peyer's patch venules
|
hematopoietic system
|
• labeled splenocytes have slightly less migration rate to the small and large intestine after intravenous injection into congenic hosts
• migration is increased when splenocytes are pretreated with pertussis toxin
|
|
• splenocytes and memory T cells persistently exhibit firm adhesion to MadCAM coated surfaces even in presence of calcium ions that normally inhibit binding
• five fold more splenocytes are found to be "sticking" to Peyer's patch venules
|
