Phenotypes associated with this allele

• Allele Symbol: Bex1^{Gt(OST125186)Lex}
• Allele Name: gene trap OST125186, Lexicon Genetics
• Allele ID: MGI:3764914
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Bex1^Gt(OST125186)Lex/Bex1^Gt(OST125186)Lex	involves: 129S5/SvEvBrd	MGI:3764917

Genotype
MGI:3764917

hm1

• Allelic Composition: Bex1^{Gt(OST125186)Lex}/Bex1^{Gt(OST125186)Lex}
• Genetic Background: involves: 129S5/SvEvBrd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

impaired exercise endurance ( J:127357 )

♀ • treadmill exercise performance and time to exhaustion are reduced by about 24% compared to wild-type mice

muscle

abnormal skeletal muscle regeneration ( J:127357 )

♀ • after injury with cardiotoxin, skeletal muscle proliferation is enhanced and prolonged and differentiation is delayed compared to wild-type controls

behavior/neurological

impaired exercise endurance ( J:127357 )

♀ • treadmill exercise performance and time to exhaustion are reduced by about 24% compared to wild-type mice