mortality/aging
• average lifespan is 22.5 weeks due to bowel obstructions and bleeding
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neoplasm
• 7 to 50 fold more small intestine tumors as in wild-type controls, with the higher incidences occurring in the more distal portions of the small intestine
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digestive/alimentary system
• severe bleeding often is cause of death
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• 7 to 50 fold more small intestine tumors as in wild-type controls, with the higher incidences occurring in the more distal portions of the small intestine
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• occurring frequently in the jejunum and ileum
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• resulting from the numerous polyps in the small intestines
• major cause of death by 22.5 weeks of age
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hematopoietic system
cardiovascular system
• severe bleeding often is cause of death
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