Analysis Tools
mortality/aging
| N |
• mice survive until birth with no heart defects
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nervous system
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• at E17.5, mice exhibit a shift in the proportional volume of the dorsal and ventral telencephalon
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• the neocortical plate is thinned in the medial and lateral regions extending throughout the rostro-caudal axis of the brain and includes the hippocampus
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• the ventral-lateral boundaries of the neocortex and palaeocortex terminate in more dorsa positions
• axonal projections linking opposing cortical hemispheres are altered compared to in wild-type mice
• axons between the thalamus and cortex are more highly represented than in wild-type mice
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craniofacial
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• at E17.5, palatal shelves do not meet at the midline (Sup. Fig. 1e)
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• at E17.5 mice exhibit secondary cleft palate
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digestive/alimentary system
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• at E17.5, palatal shelves do not meet at the midline (Sup. Fig. 1e)
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• at E17.5 mice exhibit secondary cleft palate
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growth/size/body
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• at E17.5, palatal shelves do not meet at the midline (Sup. Fig. 1e)
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• at E17.5 mice exhibit secondary cleft palate
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