mortality/aging
• mice begin to die at E10.5 and none are born
|
embryo
• at E10.5, 2 of 5 mice are smaller than wild-type
|
• at E10.5, all embryos exhibit necrosis compared to no wild-type mice
|
cardiovascular system
• at E10.5, 1 of 5 mice exhibited an irregular heartbeat
|
growth/size/body
• at E10.5, 2 of 5 mice are smaller than wild-type
|