All Phenotypes hlb243 MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

hlb243
heart, lung, and blood, 243
MGI:3767002

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	hlb243/hlb243	C57BL/6J-hlb243/J	MGI:3767003

Allelic Composition	hlb243/hlb243
Genetic Background	C57BL/6J-hlb243/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
hlb243 mutation (1 available); any hlb243 mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

increased circulating cholesterol level ( J:82961 )

• at 13 weeks of age, after consuming an atherogenic diet for >5 weeks, a homozygous mutant mouse had a 4-hour fasted plasma total cholesterol level of 517 mg/dl

increased circulating HDL cholesterol level ( J:82961 )

• at 13 weeks of age, after consuming an atherogenic diet for >5 weeks, a homozygous mutant mouse had a 4-hour fasted plasma HDL cholesterol level of 129 mg/dl

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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