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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Paxip1tm2Gdr
targeted mutation 1, Gregory R Dressler
MGI:3767658
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Paxip1tm2Gdr/Paxip1tm2Gdr involves: 129S1/Sv * 129X1/SvJ MGI:3767664
cn2
 		Paxip1tm2Gdr/Paxip1tm2Gdr
Tg(Nes-cre)1Atp/? 		involves: 129S1/Sv * 129X1/SvJ * FVB/N MGI:3767665


Genotype
MGI:3767664
hm1
Allelic
Composition		 Paxip1tm2Gdr/Paxip1tm2Gdr
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Paxip1tm2Gdr mutation (1 available); any Paxip1 mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:128440 )
• mice have no distinguishable phenotype




Genotype
MGI:3767665
cn2
Allelic
Composition		 Paxip1tm2Gdr/Paxip1tm2Gdr
Tg(Nes-cre)1Atp/?
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Paxip1tm2Gdr mutation (1 available); any Paxip1 mutation (47 available)
Tg(Nes-cre)1Atp mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
neonatal lethality, complete penetrance ( J:128440 )
• no mice survive more than a day after birth associated with reduced histone methyation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory