Analysis Tools
vision/eye
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• all long wave and nearly all short wave cones are lost
• however, the retinal is otherwise normal
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• mice lack the occasional large presynaptic swellings with multiple ribbon synapses found in wild-type mice
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• mice exhibit no detectable response to square wave stimulus at increased intensity of stimulus
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homeostasis/metabolism
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• unlike wild-type mice, both the superior and inferior retina are unresponsive to L-(+)-2-amino-4-phosphonobutyric acid (APB) treatment
• however, the APB-resistance behavior of the rod signal is normal
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nervous system
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• all long wave and nearly all short wave cones are lost
• however, the retinal is otherwise normal
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