About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Twist1tm2Bhr
targeted mutation 2, Richard R Behringer
MGI:3768516
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Twist1tm2Bhr/Twist1tm2Bhr involves: 129S7/SvEvBrd * C57BL/6J MGI:3768520
ht2
 		Twist1tm1Bhr/Twist1tm2Bhr involves: 129S7/SvEvBrd * C57BL/6J MGI:3768524


Genotype
MGI:3768520
hm1
Allelic
Composition		 Twist1tm2Bhr/Twist1tm2Bhr
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Twist1tm2Bhr mutation (1 available); any Twist1 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
skeleton phenotype ( J:128714 )
N
• mice do not exhibit any hindlimb polydactyly




Genotype
MGI:3768524
ht2
Allelic
Composition		 Twist1tm1Bhr/Twist1tm2Bhr
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Twist1tm1Bhr mutation (4 available); any Twist1 mutation (18 available)
Twist1tm2Bhr mutation (1 available); any Twist1 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
short temporal bone squamous part ( J:128714 )
• in all mice at E18.5

limbs/digits/tail
polydactyly ( J:128714 )
• at E18.5, 10 of 20 mice exhibit hindlimb polydactyly

skeleton
short temporal bone squamous part ( J:128714 )
• in all mice at E18.5




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory