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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Tyr-DT)3Bee
transgene insertion 3, Friedrich Beemann
MGI:3768646
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Tg(Tyr-DT)3Bee/?
Tg(Tyr-NRAS*Q61K)1Bee/?
involves: C57BL/6 * DBA/2 MGI:3768650
tg2
Tg(Tyr-DT)3Bee/Tg(Tyr-DT)3Bee involves: C57BL/6 * DBA/2 MGI:3768647
tg3
Tg(Tyr-DT)3Bee/? involves: C57BL/6 * DBA/2 MGI:3768648


Genotype
MGI:3768650
cx1
Allelic
Composition
Tg(Tyr-DT)3Bee/?
Tg(Tyr-NRAS*Q61K)1Bee/?
Genetic
Background
involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Tyr-DT)3Bee mutation (0 available)
Tg(Tyr-NRAS*Q61K)1Bee mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• mice seem normal and have normal skin




Genotype
MGI:3768647
tg2
Allelic
Composition
Tg(Tyr-DT)3Bee/Tg(Tyr-DT)3Bee
Genetic
Background
involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• choroidal pigment cells are absent
• however, the retinal pigment layer is present

vision/eye
• choroidal pigment cells are absent
• however, the retinal pigment layer is present




Genotype
MGI:3768648
tg3
Allelic
Composition
Tg(Tyr-DT)3Bee/?
Genetic
Background
involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• very few pigmented cells remain
• however, the retinal pigment layer is present
• nearly all pigmentation is lost likely due to the ablation of melanocytes
• mice are black-eyed with white coats

vision/eye
• very few pigmented cells remain
• however, the retinal pigment layer is present





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory