Phenotypes associated with this allele

• Allele Symbol: Naip5^Lgn1-s
• Allele Name: Legionella, susceptiblility 1
• Allele ID: MGI:3769036
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Naip5^Lgn1-s/Naip5^Lgn1-s	A/J	MGI:3769107

Genotype
MGI:3769107

hm1

• Allelic Composition: Naip5^Lgn1-s/Naip5^Lgn1-s
• Genetic Background: A/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased susceptibility to bacterial infection ( J:20633 )

• peritoneal macrophages derived from A/J mice are susceptible to Legionella pneumophilia infection; infected macrophages show a 10-fold increase in bacterial burden after 1 day of infection compared to resistant controls (C57BL/6J)