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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Csrnp1tm1Jni
targeted mutation 1, James N Ihle
MGI:3770130
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Csrnp1tm1Jni/Csrnp1tm1Jni involves: 129P2/OlaHsd * C57BL/6 MGI:3770134
cx2
 		Csrnp3tm1Jni/Csrnp3tm1Jni
Csrnp1tm1Jni/Csrnp1+
Csrnp2tm1Jni/Csrnp2tm1Jni 		involves: 129P2/OlaHsd * C57BL/6 MGI:3770137
cx3
 		Csrnp1tm1Jni/Csrnp1tm1Jni
Csrnp2tm1Jni/Csrnp2tm1Jni 		involves: 129P2/OlaHsd * C57BL/6 MGI:3770138
cx4
 		Csrnp3tm1Jni/Csrnp3tm1Jni
Csrnp1tm1Jni/Csrnp1tm1Jni
Csrnp2tm1Jni/Csrnp2tm1Jni 		involves: 129P2/OlaHsd * C57BL/6 MGI:3770140


Genotype
MGI:3770134
hm1
Allelic
Composition		 Csrnp1tm1Jni/Csrnp1tm1Jni
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Csrnp1tm1Jni mutation (0 available); any Csrnp1 mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
embryo phenotype ( J:129366 )
N
• mice exhibit normal development, hematopoiesis and T cell function

hematopoietic system
hematopoietic system phenotype ( J:129366 )
N
• mice exhibit normal development, hematopoiesis and T cell function

immune system
immune system phenotype ( J:129366 )
N
• mice exhibit normal development, hematopoiesis and T cell function




Genotype
MGI:3770137
cx2
Allelic
Composition		 Csrnp3tm1Jni/Csrnp3tm1Jni
Csrnp1tm1Jni/Csrnp1+
Csrnp2tm1Jni/Csrnp2tm1Jni
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Csrnp1tm1Jni mutation (0 available); any Csrnp1 mutation (39 available)
Csrnp2tm1Jni mutation (0 available); any Csrnp2 mutation (19 available)
Csrnp3tm1Jni mutation (0 available); any Csrnp3 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, incomplete penetrance ( J:129366 )
• survival rates range between 25% and 45% of expected values




Genotype
MGI:3770138
cx3
Allelic
Composition		 Csrnp1tm1Jni/Csrnp1tm1Jni
Csrnp2tm1Jni/Csrnp2tm1Jni
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Csrnp1tm1Jni mutation (0 available); any Csrnp1 mutation (39 available)
Csrnp2tm1Jni mutation (0 available); any Csrnp2 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
embryo phenotype ( J:129366 )
N
• mice exhibit normal development, hematopoiesis and T cell function

hematopoietic system
hematopoietic system phenotype ( J:129366 )
N
• mice exhibit normal development, hematopoiesis and T cell function

immune system
immune system phenotype ( J:129366 )
N
• mice exhibit normal development, hematopoiesis and T cell function




Genotype
MGI:3770140
cx4
Allelic
Composition		 Csrnp3tm1Jni/Csrnp3tm1Jni
Csrnp1tm1Jni/Csrnp1tm1Jni
Csrnp2tm1Jni/Csrnp2tm1Jni
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Csrnp1tm1Jni mutation (0 available); any Csrnp1 mutation (39 available)
Csrnp2tm1Jni mutation (0 available); any Csrnp2 mutation (19 available)
Csrnp3tm1Jni mutation (0 available); any Csrnp3 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality ( J:129366 )
• the majority of mice die within the first 48 hours after birth




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory