behavior/neurological
• female, but not male, mice exhibit reduced preference for a natural reward in sucrose preference tests compared to wild-type mice
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• female, but not male, mice exhibit more immobility when placed in swim test than wild-type mice
• unlike wild-type mice, female and male mice do not exhibit any decrease in immobility following administration of desipramine
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• male, but not female, mice exhibit increased locomotor activity compared to same sex wild-type mice
• however, activity levels are normal after 4 days of habituation
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