Phenotypes associated with this allele

• Allele Symbol: Tead4^tm1Hssk
• Allele Name: targeted mutation 1, Hiroshi Sasaki
• Allele ID: MGI:3770620
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tead4^tm1Hssk/Tead4^tm1Hssk	either: (involves: C57BL/6 * CBA) or (involves: C57BL/6 * CBA * DBA)	MGI:5485031

Genotype
MGI:5485031

hm1

• Allelic Composition: Tead4^tm1Hssk/Tead4^tm1Hssk
• Genetic Background: either: (involves: C57BL/6 * CBA) or (involves: C57BL/6 * CBA * DBA)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality before implantation, complete penetrance ( J:130047 )

• no embryos are recovered at post-implantation stages

embryo

abnormal preimplantation embryo development ( J:130047 )

absent blastocoele ( J:130047 )

• embryos fail to form clear blastocoeles

• however, cell proliferation is normal

absent trophoblast giant cells ( J:130047 )

absent trophectoderm ( J:130047 )

• embryos fail to form trophectoderm