Phenotypes associated with this allele

• Allele Symbol: bdd
• Allele Name: bulging disc disease
• Allele ID: MGI:3770627
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	bdd/bdd	STOCK bdd/J	MGI:3817965

Genotype
MGI:3817965

hm1

• Allelic Composition: bdd/bdd
• Genetic Background: STOCK bdd/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

bdd/bdd mice show degenerative inter-vertebral disk material protruding dorsally, displacing the overlying spinal cord

skeleton

abnormal pelvic girdle bone morphology ( J:141134 )

• horseshoe shaped hips evident by 3 weeks of age

abnormal intervertebral disk morphology ( J:141134 )

prolapsed intervertebral disk ( J:141134 )

• prolapsed discs are found by 1 year of age

growth/size/body

decreased body size ( J:141134 )

• evident by 3 weeks of age

hearing/vestibular/ear

increased or absent threshold for auditory brainstem response ( J:141134 )

• at 156 days homozygotes exhibit ABR thresholds about 30 dB above those of heterozygous controls

• a 248 day old homozygous mutant mouse exhibited a 40 dB increase in ABR thresholds

vision/eye

abnormal iris morphology ( J:141134 )

abnormal cornea morphology ( J:141134 )

abnormal retina morphology ( J:141134 )