About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
malf
malformed ear
MGI:3770630
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
malf/malf CXB5/ByJ-malf/J MGI:5661936


Genotype
MGI:5661936
hm1
Allelic
Composition
malf/malf
Genetic
Background
CXB5/ByJ-malf/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
malf mutation (1 available); any malf mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

malf/malf mouse with one misplaced ear and a twisted snout

craniofacial
• some of the homozygotes with a misplaced or malformed ear also have assymmetry of the snout that can be a very noticeable twist
• ear pinnae can be smaller than normal or misshapen
• one or both ears can be positioned lower than normal and which ear is affected is not impacted by the phenotype of the parents
• of 37 mutants 28 had the left pinna affected, 8 had the right pinna affected and 1 had both affected

hearing/vestibular/ear
• ear pinnae can be smaller than normal or misshapen
• one or both ears can be positioned lower than normal and which ear is affected is not impacted by the phenotype of the parents
• of 37 mutants 28 had the left pinna affected, 8 had the right pinna affected and 1 had both affected

growth/size/body
• some of the homozygotes with a misplaced or malformed ear also have assymmetry of the snout that can be a very noticeable twist
• ear pinnae can be smaller than normal or misshapen
• one or both ears can be positioned lower than normal and which ear is affected is not impacted by the phenotype of the parents
• of 37 mutants 28 had the left pinna affected, 8 had the right pinna affected and 1 had both affected





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory