Phenotypes associated with this allele

• Allele Symbol: Gsk3a^tm1.1Jrw
• Allele Name: targeted mutation 1.1, James R Woodgett
• Allele ID: MGI:3771223
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gsk3a^tm1.1Jrw/Gsk3a^tm1.1Jrw	involves: 129S6/SvEvTac * C57BL/6	MGI:3771289

Genotype
MGI:3771289

hm1

• Allelic Composition: Gsk3a^tm1.1Jrw/Gsk3a^tm1.1Jrw
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

improved glucose tolerance ( J:130033 )

increased liver glycogen level ( J:130033 )

• fasted hepatic glycogen deposition is increased compared to in wild-type mice

• however, fasted glycogen levels in muscle and epididymal fat are normal

increased insulin sensitivity ( J:130033 )

growth/size/body

increased lean body mass ( J:130033 )

adipose tissue

decreased percent body fat/body weight ( J:130033 )

• total body fat is reduced

liver/biliary system

increased liver glycogen level ( J:130033 )

• fasted hepatic glycogen deposition is increased compared to in wild-type mice

• however, fasted glycogen levels in muscle and epididymal fat are normal