Phenotypes associated with this allele

• Allele Symbol: Ehmt2^Gt(ES62)Feil
• Allele Name: gene trap ES62, Robert Feil
• Allele ID: MGI:3772197
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ehmt2^Gt(ES62)Feil/Ehmt2^Gt(ES62)Feil	involves: 129P2/OlaHsd * C57BL/6	MGI:3772206

Genotype
MGI:3772206

hm1

• Allelic Composition: Ehmt2^Gt(ES62)Feil/Ehmt2^Gt(ES62)Feil
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:130398 )

• mice are present up to E10

embryo

decreased embryo size ( J:130398 )

• at E8.5 to E9.5, mice are half the size of wild-type mice

open neural tube ( J:130398 )

decreased trophoblast giant cell number ( J:130398 )

• there is an 18% decrease in the number of giant cells and 2-fold increase in giant cell apoptosis compared to in wild-type mice

small placenta ( J:130398 )

• placenta diameter is reduced 10% compared to wild-type placenta

nervous system

open neural tube ( J:130398 )

growth/size/body

decreased embryo size ( J:130398 )

• at E8.5 to E9.5, mice are half the size of wild-type mice

cellular

abnormal imprinting ( J:130398 )

• imprinting in the placenta is lost

• however, imprinting in the embryo is normal