Phenotypes associated with this allele

• Allele Symbol: Pax4^{tm1(cre/ERT2)Sosa}
• Allele Name: targeted mutation 1, Beatriz Sosa-Pineda
• Allele ID: MGI:3772207
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pax4^tm1(cre/ERT2)Sosa/Pax4^tm1(cre/ERT2)Sosa	Not Specified	MGI:3772208

Genotype
MGI:3772208

hm1

• Allelic Composition: Pax4^{tm1(cre/ERT2)Sosa}/Pax4^{tm1(cre/ERT2)Sosa}
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:130423 )

• mice die 3 days after birth

endocrine/exocrine glands

abnormal pancreas morphology ( J:130423 )

• pancreas is deficient in insulin+ or somatostatin+ cells but contain an abundance of glucagon+ cells or ghrelin+ cells

absent pancreatic beta cells ( J:130423 )

• pancreas is deficient in insulin+ cells

absent pancreatic delta cells ( J:130423 )

• pancreas is deficient in somatostatin+ cells

growth/size/body

decreased body size ( J:130423 )