Phenotypes associated with this allele

• Allele Symbol: Sgca^tm2.1Kcam
• Allele Name: targeted mutation 2.1, Kevin P Campbell
• Allele ID: MGI:3772335
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sgca^tm2.1Kcam/Sgca^tm2.1Kcam	either: (involves: 129S4/SvJae * 129S6/SvEvTac) or (involves: 129S6/SvEvTac * C57BL/6J * FVB/N)	MGI:3772353

Genotype
MGI:3772353

hm1

• Allelic Composition: Sgca^tm2.1Kcam/Sgca^tm2.1Kcam
• Genetic Background: either: (involves: 129S4/SvJae * 129S6/SvEvTac) or (involves: 129S6/SvEvTac * C57BL/6J * FVB/N)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

muscle phenotype ( J:130252 )

N • mice do not develop muscular dystrophy; the mutant alpha-sarcoglycan is expressed at the sarcolemma at levels similar to wild-type and with similar transcription efficiency

N • creatine kinase levels are normal at baseline and following exercise; sarcolemmal membrane damage is not exhibited by fibers

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:130252 )

N • serum creatine kinase levels are normalized