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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rtel1tm1Hdin
targeted mutation 1, Hao Ding
MGI:3772370
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rtel1tm1Hdin/Rtel1tm1Hdin involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL MGI:3772440
cn2
 		Rtel1tm1Hdin/Rtel1tm1Hdin involves: 129S1/Sv * 129X1/SvJ MGI:5559536


Genotype
MGI:3772440
hm1
Allelic
Composition		 Rtel1tm1Hdin/Rtel1tm1Hdin
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rtel1tm1Hdin mutation (0 available); any Rtel1 mutation (75 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:130490 )
• mice are healthy and fertile




Genotype
MGI:5559536
cn2
Allelic
Composition		 Rtel1tm1Hdin/Rtel1tm1Hdin
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rtel1tm1Hdin mutation (0 available); any Rtel1 mutation (75 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
decreased DNA replication ( J:202812 )
• decreased fork speed and instability in mouse embryonic fibroblasts transfected with a cre-expressing adenovirus

homeostasis/metabolism
decreased DNA replication ( J:202812 )
• decreased fork speed and instability in mouse embryonic fibroblasts transfected with a cre-expressing adenovirus




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory