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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Agtpbp1pcd-8J
Purkinje cell degeneration 8 Jackson
MGI:3772649
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Agtpbp1pcd-8J/Agtpbp1pcd-8J BALB/cJ-Agtpbp1pcd-8J/GrsrJ MGI:3776121


Genotype
MGI:3776121
hm1
Allelic
Composition		 Agtpbp1pcd-8J/Agtpbp1pcd-8J
Genetic
Background		 BALB/cJ-Agtpbp1pcd-8J/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agtpbp1pcd-8J mutation (0 available); any Agtpbp1 mutation (66 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
ataxia ( J:132487 )
• moderate ataxia found by 3 to 4 weeks of age

growth/size/body
decreased body size ( J:132487 )

nervous system

reproductive system
abnormal male germ cell morphology ( J:132487 )
• abnormal sperm in one 19 week old male
reduced female fertility ( J:132487 )
• females are very poor breeders
male infertility ( J:132487 )
• males do not breed

vision/eye
abnormal retina layer morphology ( J:132487 )
• thin retinal vessels found in one 4 month old female and low rod and cone detection in one 6 week old male

cellular
abnormal male germ cell morphology ( J:132487 )
• abnormal sperm in one 19 week old male




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory