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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Kcnq1ot1tm2Mjh
targeted mutation 2, Michael J Higgins
MGI:3772666
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Kcnq1ot1tm2Mjh/Kcnq1ot1+ involves: 129S4/SvJae * C57BL/6 * FVB/N MGI:3772669


Genotype
MGI:3772669
ht1
Allelic
Composition
Kcnq1ot1tm2Mjh/Kcnq1ot1+
Genetic
Background
involves: 129S4/SvJae * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
embryo
• at E15.5, mice that inherit the paternal allele are 11% smaller than wild-type mice
• at E15.5, mice that inherit the paternal allele exhibit a 14% reduction in placenta compared to wild-type

growth/size/body
• at E15.5, mice that inherit the paternal allele are 11% smaller than wild-type mice
• at E15.5, mice that inherit the paternal allele are 7% smaller than wild-type mice

cellular
• expression of several maternally imprinted genes under the control of the Kcnq imprinting control region is disrupted





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory