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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Klra8Cmv1-del
cytomegalovirus resistance 1, deletion
MGI:3773165
Summary 3 genotypes


Genotype
MGI:3796335
ht1
Allelic
Composition		 Klra8Cmv1-del/Klra8Cmv1-s
Genetic
Background		 (BXD8/TyJ x BALB/c)F1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klra8Cmv1-del mutation (2 available); any Klra8 mutation (18 available)
Klra8Cmv1-s mutation (0 available); any Klra8 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased susceptibility to Herpesvirales infection ( J:79093 )
• Background Sensitivity: all mice from this F1 cross are susceptible to CMV infection as measured by viral load in the spleen three days after infection




Genotype
MGI:3796336
ht2
Allelic
Composition		 Klra8Cmv1-del/Klra8Cmv1-r
Genetic
Background		 (BXD8/TyJ x C57BL/6)F1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klra8Cmv1-del mutation (2 available); any Klra8 mutation (18 available)
Klra8Cmv1-r mutation (3 available); any Klra8 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to Herpesvirales infection ( J:79093 )
• Background Sensitivity: all mice from this F1 cross are resistant to CMV infection as measured by viral load in the spleen three days after infection




Genotype
MGI:3796337
ht3
Allelic
Composition		 Klra8Cmv1-del/Klra8Cmv1-s
Genetic
Background		 (BXD8/TyJ x DBA/2)F1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klra8Cmv1-del mutation (2 available); any Klra8 mutation (18 available)
Klra8Cmv1-s mutation (0 available); any Klra8 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased susceptibility to Herpesvirales infection ( J:79093 )
• Background Sensitivity: all mice from this F1 cross are susceptible to CMV infection as measured by viral load in the spleen three days after infection




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory