Phenotypes associated with this allele

• Allele Symbol: Stk36^tm1.1Ptch
• Allele Name: targeted mutation 1.1, Pao-Tien Chuang
• Allele ID: MGI:3773685
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Stk36^tm1.1Ptch/Stk36^tm1.1Ptch	involves: 129P2/OlaHsd * C57BL/6 * FVB/N * Swiss Webster	MGI:3775657

Genotype
MGI:3775657

hm1

• Allelic Composition: Stk36^tm1.1Ptch/Stk36^tm1.1Ptch
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * Swiss Webster

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:131268 )

• homozygotes thrive initially after birth, but become visibly runted by day 7, and appear emaciated with the majority dying before 3 weeks of age; lethality appears to be completely penetrant

growth/size/body

decreased body weight ( J:131268 )

• mice fail to gain weight at normal rate after birth, becoming runted and appearing emaciated after day 7

postnatal growth retardation ( J:131268 )

• mice fail to gain weight and grow after birth;

• before birth, homozygotes appear normal and display no defects in development or organogenesis