Phenotypes associated with this allele

• Allele Symbol: Prrx1^tm1Bhr
• Allele Name: targeted mutation 1, Richard R Behringer
• Allele ID: MGI:3773688
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prrx1^tm1Bhr/Prrx1^tm1Bhr	involves: 129S/SvEv * 129S4/SvJae * C57BL/6	MGI:3775632

Genotype
MGI:3775632

hm1

• Allelic Composition: Prrx1^tm1Bhr/Prrx1^tm1Bhr
• Genetic Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

long limbs ( J:131364 )

• limbs on average are 6% longer than wild-type at E18.5

skeleton

abnormal long bone hypertrophic chondrocyte zone ( J:131364 )

• mitotic index of chondrocytes of humerus is increased by 6% relative to controls at E17.5

decreased width of hypertrophic chondrocyte zone ( J:131364 )

• zone is reduced and expanded trabecular bone is found at E17.5

abnormal trabecular bone morphology ( J:131364 )

• trabecular bone of humerus is significantly expanded relative to wild-type