Phenotypes associated with this allele

• Allele Symbol: Dab1^scm-3J
• Allele Name: scrambler 3 Jackson
• Allele ID: MGI:3773692
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dab1^scm-3J/Dab1^scm-3J	B6.Cg-Dab1^scm-3J/J	MGI:3849293

Genotype
MGI:3849293

hm1

• Allelic Composition: Dab1^scm-3J/Dab1^scm-3J
• Genetic Background: B6.Cg-Dab1^scm-3J/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Cerebellum hypoplasia and hippocampus disorganization in Dab1^scm-3J/Dab1^scm-3J mice

mortality/aging

postnatal lethality, incomplete penetrance ( J:149813 )

• homozygotes rarely survive beyond 3 weeks of age

behavior/neurological

abnormal motor coordination/balance ( J:149813 )

• at approximately 2 weeks of age homozygotes are severely unstable in their gait and unable to right themselves

impaired righting response ( J:149813 )

nervous system

absent cerebellar foliation ( J:149813 )

abnormal hippocampus layer morphology ( J:149813 )

• disorganization of the hippocampal layers

cerebellum hypoplasia ( J:149813 )

growth/size/body

decreased body size ( J:149813 )

• evident by 14 days of age