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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Leprtm3(cre)Mgmj
targeted mutation 1, Martin G Myers, Jr
MGI:3773731
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Leprtm3(cre)Mgmj/Leprtm3(cre)Mgmj involves: 129S1/Sv * 129X1/SvJ MGI:3813249
cn2
 		Irs2tm2Mfw/Irs2tm2Mfw
Irs4tm1.1Mfw/Y
Leprtm3(cre)Mgmj/Lepr+ 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:5705239


Genotype
MGI:3813249
hm1
Allelic
Composition		 Leprtm3(cre)Mgmj/Leprtm3(cre)Mgmj
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Leprtm3(cre)Mgmj mutation (1 available); any Lepr mutation (122 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
growth/size/body region phenotype ( J:131433 )
N
• mice exhibit normal body weight




Genotype
MGI:5705239
cn2
Allelic
Composition		 Irs2tm2Mfw/Irs2tm2Mfw
Irs4tm1.1Mfw/Y
Leprtm3(cre)Mgmj/Lepr+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Irs2tm2Mfw mutation (0 available); any Irs2 mutation (37 available)
Irs4tm1.1Mfw mutation (0 available); any Irs4 mutation (5 available)
Leprtm3(cre)Mgmj mutation (1 available); any Lepr mutation (122 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
homeostasis/metabolism phenotype ( J:221293 )
N
• blood glucose levels are similar to controls

growth/size/body
growth/size/body region phenotype ( J:221293 )
N
• body weight is essentially similar to homozygous Irs2tm2Mfw / heterozygous Leprtm3(cre)Mgmj male mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory