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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gper1tm1Cwan
targeted mutation 1, Chunhe Wang
MGI:3773753
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gper1tm1Cwan/Gper1tm1Cwan involves: 129S6/SvEvTac * C57BL/6J MGI:3812538


Genotype
MGI:3812538
hm1
Allelic
Composition		 Gper1tm1Cwan/Gper1tm1Cwan
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gper1tm1Cwan mutation (1 available); any Gper1 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal response/metabolism to endogenous compounds ( J:131313 )
• thymic atrophy induced by E2 treatment is attenuated compared to in similarly treated wild type mice
• E2 induced apoptosis of TCRbeta-/low DP thymocytes is attenuated compared to in wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory