About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Akr1c18tm1Mni
targeted mutation 1, Masugi Nishihara
MGI:3774264
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Akr1c18tm1Mni/Akr1c18tm1Mni involves: 129P2/OlaHsd * C57BL/6J MGI:3800787


Genotype
MGI:3800787
hm1
Allelic
Composition
Akr1c18tm1Mni/Akr1c18tm1Mni
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Akr1c18tm1Mni mutation (2 available); any Akr1c18 mutation (29 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• pregnancy is prolonged by 2 days in 2 of 11 mutants and by 1 day in 3 mutants and pseudopregnancy is extended by 2.5 days
• duration of continuous diestrus is prolonged by about 1.5 days
• the number of pups, especially live pups, is decreased

homeostasis/metabolism
• serum progesterone levels do decline before parturition as in wild-type and are low enough for delivery of pups, however levels are still 1.3 times higher than in wild-type





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/19/2024
MGI 6.24
The Jackson Laboratory