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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rettm14(Gfra1)Jmi
targeted mutation 14, Jeffrey Milbrandt
MGI:3774316
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Rettm14(Gfra1)Jmi/Ret+ involves: 129X1/SvJ MGI:3801031
cx2
 		Gfra1tm3Jmi/Gfra1tm3Jmi
Rettm14(Gfra1)Jmi/Ret+ 		involves: 129X1/SvJ MGI:3801035


Genotype
MGI:3801031
ht1
Allelic
Composition		 Rettm14(Gfra1)Jmi/Ret+
Genetic
Background		 involves: 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rettm14(Gfra1)Jmi mutation (0 available); any Ret mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:130616 )
• heterozygotes grow normally without overt deficits in the enteric system or kidney




Genotype
MGI:3801035
cx2
Allelic
Composition		 Gfra1tm3Jmi/Gfra1tm3Jmi
Rettm14(Gfra1)Jmi/Ret+
Genetic
Background		 involves: 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gfra1tm3Jmi mutation (0 available); any Gfra1 mutation (33 available)
Rettm14(Gfra1)Jmi mutation (0 available); any Ret mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:130616 )
• mutants exhibit no deficits in enteric neurons, motor neurons, Schwann cells, regenerating nerves, ureteric bud and kidney development and no abnormalities in the olfactory bulb




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory