Phenotypes associated with this allele

• Allele Symbol: Eif2ak4^tm1.1Dron
• Allele Name: targeted mutation 1.1, David Ron
• Allele ID: MGI:3774318
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Eif2ak4^tm1.1Dron/Eif2ak4^tm1.1Dron Tg(Nes-cre)1Kln/0	involves: 129S6/SvEvTac * C57BL/6 * SJL	MGI:3806277

Genotype
MGI:3806277

cn1

• Allelic Composition: Eif2ak4^tm1.1Dron/Eif2ak4^tm1.1Dron; Tg(Nes-cre)1Kln/0
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal food preference ( J:129841 )

• mice have much less of an aversion to diets lacking an essential amino acid

• mice consume more of a leucine-deficient chow after 1 hour compared to wild-type mice that consume almost 30% less

• mice consume under 10% less leucine-deficient chow after 4 hours compared to wild-type mice that consume around 25% less

• similar responses are observed in threonine-deficient diet