Phenotypes associated with this allele

• Allele Symbol: Mylpf^tm1Jdp
• Allele Name: targeted mutation 1, James D Potter
• Allele ID: MGI:3774323
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mylpf^tm1Jdp/Mylpf^tm1Jdp	involves: 129S6/SvEvTac * C57BL/6	MGI:3801063

Genotype
MGI:3801063

hm1

• Allelic Composition: Mylpf^tm1Jdp/Mylpf^tm1Jdp
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:131461 )

• die immediately after birth most likely due to respiratory failure because diaphragms lack skeletal muscle

growth/size/body

decreased body weight ( J:131461 )

• body weight of newborns is decreased 30% compared to wild-type or heterozygous mice

muscle

absent skeletal muscle ( J:131461 )

• complete lack of both fast and slow skeletal muscle

respiratory system

respiratory failure ( J:131461 )

cardiovascular system

cardiovascular system phenotype ( J:131461 )

N • hearts of newborns are normal in size and weight, indicating no defects in cardiac muscle