All Phenotypes Tnfrsf10b<tm1.1Cjk> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tnfrsf10b^tm1.1Cjk
targeted mutation 1.1, Christopher J Kemp
MGI:3774334

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tnfrsf10b^tm1.1Cjk/Tnfrsf10b^tm1.1Cjk	involves: 129P2/OlaHsd * BALB/c * NIH/OlaHsd	MGI:3778919

Allelic Composition	Tnfrsf10b^tm1.1Cjk/Tnfrsf10b^tm1.1Cjk
Genetic Background	involves: 129P2/OlaHsd * BALB/c * NIH/OlaHsd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tnfrsf10b^tm1.1Cjk mutation (0 available); any Tnfrsf10b mutation (29 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased metastatic potential ( J:130806 )

• 45 weeks after induction of skin tumors, there is a significantly higher incidence of metastasis into the lymph nodes

• 32% of mice have lymph node metastasis 50 weeks after skin cancer induction compared to only 9% in wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24