Phenotypes associated with this allele

• Allele Symbol: Avil^{tm1(ALPP)Fawa}
• Allele Name: targeted mutation 1, Fan Wang
• Allele ID: MGI:3774413
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Avil^tm1(ALPP)Fawa/Avil^tm1(ALPP)Fawa	involves: 129P2/OlaHsd	MGI:3789611

Genotype
MGI:3789611

hm1

• Allelic Composition: Avil^{tm1(ALPP)Fawa}/Avil^{tm1(ALPP)Fawa}
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased survivor rate ( J:130971 )

• less than expected Mendelian ratio of homozygous mice are born, indicating approximately half of homozygous mice are lethal at embryonic stages

• the surviving homozygous animals are fertile and do not show any detectable abnormal behaviors

prenatal lethality, incomplete penetrance ( J:130971 )

• less than expected Mendelian ratio of homozygous mice are born, indicating approximately half of homozygous mice are lethal at embryonic stages

• the surviving homozygous animals are fertile and do not show any detectable abnormal behaviors

nervous system

impaired central nervous system regeneration ( J:130971 )

• axonal regrowth of trigeminal sensory neuron in culture is significantly shorter

• abnormal remodeling pattern of trigeminal central projection after whisker cauterization