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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Del(14Ltb4r2-Ltb4r1)1Bodd
deletion, Chr 14, Bodduluri Haribabu 1
MGI:3775059
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Del(14Ltb4r2-Ltb4r1)1Bodd/Del(14Ltb4r2-Ltb4r1)1Bodd involves: 129S4/SvJaeSor * C57BL/6 MGI:3810999
ht2
Del(14Ltb4r2-Ltb4r1)1Bodd/+ involves: 129S4/SvJaeSor * C57BL/6 MGI:3811001


Genotype
MGI:3810999
hm1
Allelic
Composition
Del(14Ltb4r2-Ltb4r1)1Bodd/Del(14Ltb4r2-Ltb4r1)1Bodd
Genetic
Background
involves: 129S4/SvJaeSor * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(14Ltb4r2-Ltb4r1)1Bodd mutation (1 available); any Del(14Ltb4r2-Ltb4r1)1Bodd mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• mice exhibit normal numbers of circulating lymphocytes, monocytes, neutrophils and eosinophils and normal serum levels of IgG and IgM
• in response to Ltb4
• following treatment with collagen to induce arthritis, mice exhibit no evidence of pannus formation or fibrillation of the cartilage unlike in similarly treated wild-type mice
• however, mice do produce antibodies against collagen type II

skeleton
• following treatment with collagen to induce arthritis, mice exhibit no evidence of pannus formation or fibrillation of the cartilage unlike in similarly treated wild-type mice
• however, mice do produce antibodies against collagen type II

cellular
• in response to Ltb4

hematopoietic system
• in response to Ltb4




Genotype
MGI:3811001
ht2
Allelic
Composition
Del(14Ltb4r2-Ltb4r1)1Bodd/+
Genetic
Background
involves: 129S4/SvJaeSor * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(14Ltb4r2-Ltb4r1)1Bodd mutation (1 available); any Del(14Ltb4r2-Ltb4r1)1Bodd mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• mice exhibit reduced incidence and severity of arthritis induced by collagen compared to in similarly treated wild-type mice

skeleton
• mice exhibit reduced incidence and severity of arthritis induced by collagen compared to in similarly treated wild-type mice





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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory