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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cysltr2tm1Sish
targeted mutation 1, Satoshi Ishii
MGI:3775826
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cysltr2tm1Sish/Cysltr2tm1Sish involves: C57BL/6 MGI:3783677


Genotype
MGI:3783677
hm1
Allelic
Composition		 Cysltr2tm1Sish/Cysltr2tm1Sish
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cysltr2tm1Sish mutation (0 available); any Cysltr2 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal response to cardiac infarction ( J:132275 )
• the number of apoptotic nuclei in the peri-infarct region of the heart is 7-fold higher than in wild-type littermates 48 hours after reperfusion
• two weeks after reperfusion mice have significant thinning of the interventricular septum and increases in the time constant of isovolumic relaxation

homeostasis/metabolism
abnormal response to cardiac infarction ( J:132275 )
• the number of apoptotic nuclei in the peri-infarct region of the heart is 7-fold higher than in wild-type littermates 48 hours after reperfusion
• two weeks after reperfusion mice have significant thinning of the interventricular septum and increases in the time constant of isovolumic relaxation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory