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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		S100a1tm1Mfs
targeted mutation 1, Martin Schneider
MGI:3775945
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		S100a1tm1Mfs/S100a1tm1Mfs involves: 129S6/SvEvTac * C57BL/6 MGI:3811185


Genotype
MGI:3811185
hm1
Allelic
Composition		 S100a1tm1Mfs/S100a1tm1Mfs
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
S100a1tm1Mfs mutation (0 available); any S100a1 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
abnormal muscle physiology ( J:132177 )
• muscle fibers exhibit a 31.6% decreased peak amplitude calcium ion transient following a single action potential stimulation compared to in wild-type mice
• muscle fibers exhibit a prolonged rising phase of calcium ion transient following a single action potential stimulation compared to in wild-type mice
• however, calcium ion resting levels are normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory