Phenotypes associated with this allele

• Allele Symbol: Kng1^tm1Krmc
• Allele Name: targeted mutation 1, Keith R McCrae
• Allele ID: MGI:3776034
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kng1^tm1Krmc/Kng1^tm1Krmc	either: (involves: 129S7/SvEvBrd * C57BL/6J) or (involves: 129S7/SvEvBrd * CD-1)	MGI:3811162

Genotype
MGI:3811162

hm1

• Allelic Composition: Kng1^tm1Krmc/Kng1^tm1Krmc
• Genetic Background: either: (involves: 129S7/SvEvBrd * C57BL/6J) or (involves: 129S7/SvEvBrd * CD-1)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal blood coagulation ( J:130769 )

• procoagulant activity of plasma is much lower than that of controls when tested in deficient human plasma

increased partial thromboplastin time ( J:130769 )

• activated partial thromboplastin times are two times greater than those of controls

decreased susceptibility to induced thrombosis ( J:130769 )

• time to occlusion of the carotid artery following Rose-Bengal and laser-induced arterial injury is twice as long as in controls