Phenotypes associated with this allele

• Allele Symbol: Ahr^tm1(AHR)Mym
• Allele Name: targeted mutation 1, Masayuki Yamamoto
• Allele ID: MGI:3776466
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ahr^tm1(AHR)Mym/Ahr^tm1(AHR)Mym	B6.129P2-Ahr^tm1(AHR)Mym	MGI:3776488

Genotype
MGI:3776488

hm1

• Allelic Composition: Ahr^tm1(AHR)Mym/Ahr^tm1(AHR)Mym
• Genetic Background: B6.129P2-Ahr^tm1(AHR)Mym

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased physiological sensitivity to xenobiotic ( J:132380 )

• mice are resistant to the teratogenic effects of TCDD with no mice exhibiting altered palate development

• mice from mothers treated with TCDD exhibit a similar incidence of hydronephrosis as Ahr^b-1 homozygotes but at a reduced severity