Phenotypes associated with this allele

• Allele Symbol: Tg(tetO-S100a10)1Pggd
• Allele Name: transgene insertion 1, Paul Greengard
• Allele ID: MGI:3776629
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Tg(Camk2a-tTA)1Mmay/0 Tg(tetO-S100a10)1Pggd/0	involves: C57BL/6	MGI:3776630

Genotype
MGI:3776630

cx1

• Allelic Composition: Tg(Camk2a-tTA)1Mmay/0; Tg(tetO-S100a10)1Pggd/0
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal depression-related behavior ( J:104116 )

• mice exhibit decreased depression-related behavior such as immobility when suspended by their tails

• however, treatment with doxycycline restores normal depression-related behaviors

decreased anxiety-related response ( J:104116 )

• mice exhibit decreased thigmotaxis and increased horizontal activity in an open-field test

• however, treatment with doxycycline restores normal anxiety-related behaviors

hyperactivity ( J:104116 )