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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Zbp1tm1Aki
targeted mutation 1, Shizuo Akira
MGI:3776827
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Zbp1tm1Aki/Zbp1tm1Aki involves: C57BL/6 MGI:3776852
cx2
 		Ripk3tm2Vmd/Ripk3tm2Vmd
Zbp1tm1Aki/Zbp1tm1Aki 		involves: C57BL/6N MGI:5614633


Genotype
MGI:3776852
hm1
Allelic
Composition		 Zbp1tm1Aki/Zbp1tm1Aki
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zbp1tm1Aki mutation (0 available); any Zbp1 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:132662 )
N
• the immunogenicity generated by a DNA vaccine is normal in these mice




Genotype
MGI:5614633
cx2
Allelic
Composition		 Ripk3tm2Vmd/Ripk3tm2Vmd
Zbp1tm1Aki/Zbp1tm1Aki
Genetic
Background		 involves: C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ripk3tm2Vmd mutation (0 available); any Ripk3 mutation (34 available)
Zbp1tm1Aki mutation (0 available); any Zbp1 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality prior to tooth bud stage ( J:209137 )
• embryos do not survive beyond around E11.5




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory